Gilbert Ling in 1962
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Гильберт Линг (Gilbert Nin Ling),
создатель количественных
теорий клеточной
проницаемости,
биоэлектрических потенциалов,
окислительного
фосфорилирования.
Выдвинул
оригинальную теорию мышечного
сокращения.
Домашняя страница (home page): http://www.gilbertling.org/
E-mail: gilbertling @ dobar.org
Гильберт Нин Линг по происхождению - китаец, родился в
1919 г. В 40-х годах получил высшее образование в США по
правительственной программе помощи США Китаю. Является автором
революционного для своего времени метода - микроэлектродной техники
отведения клеточных потенциалов. Большую часть своей научной карьеры
возглавлял лабораторию в Пеннсильванском госпитале.
Является автором около 200 научных работ (из них 3 - монографии),
опубликованных в авторитетных научных журналах. Основатель научного
журнала Physiological Chemistry and Physics and Medical NMR. Усредненный
индекс цитирования работ Линга (без учета самоцитирования) в период с
1980 по 1991 г. - 6 цитирований в год. При этом в 1990 году работы Линга
цитировали в 14 публикациях; в 1991 году - в 11. Необходимо отметить,
что работ с критикой взглядов Линга крайне мало и указанные индексы
цитирования -показатель именно одобрительного внимания.
Монографии:
1. Ling, G.N.
A Physical
Theory of the Living State: The Association-Induction
Hypothesis, Waltham, Massachusetts: Blaisdell, 1962. 680
p.
2. Ling, G.N.
In Search of the Physical Basis of Life,
New York and London: Plenum Press, 1984. 791 p.
3. Ling, G.N.
A Revolution in the Physiology of the Living
Cell, Malabar, Florida: Krieger
Publishing Company, 1992. 404 p.
4. Ling G.N.
"Life at the Cell and Below-Cell Level: the Hidden
History of a
Fundamental Revolution in Biology".
Книга переведена
на русский язык.
Main principles of Ling’s physical theory of the living cell
"A PHYSICAL THEORY OF THE LIVING STATE:
the Association-Induction Hypothesis with Considerations
of the Mechanisms Involved in Ionic Specificity, Behavior
of Proteins, Selective Accumulation of Ions and
Nonelectrolytes, Cellular Electrical Potentials, Ionic
Permeability and Diffusion, Excitation and Inhibition,
Contractile Mechanism, Enzyme Action, Drug and Hormone
Action, Antibody-Antigen Reaction, Fertilization,
Chemical Embryology, Growth, Differentiation, and
Cancer."
GILBERT N. LING
"Ling offers no less than... a general molecular
theory of life phenomena... a major synthesis, moving
from the minor variables at the molecular level to the
major properties of the cellular level... Such an
integrative and synthetic treatment cannot fail to give
the whole field of biology a great forward impetus."
RALPH W. GERARD, University of Michigan
"At a time when we look forward to the merging of
the physical and biological sciences, this is a most
stimulating book, distinguished by a bold and inquisitive
attitude on the one hand, and careful experimental
methods on the other."
C.N. YANG, Nobel Laureate in Physics, 1957
GILBERT N. LING, born in 1919, a native of China, entered
the National Central University in Chungking as a student
of animal husbandry. After two years, he transferred to
the biology department and received a B.Sc. degree in
1943. Having done graduate work in zoology at the Tsing
Hua University in Kunming, he won the Boxer Indemnity
Fellowship, in 1945, to study physiology in the United
States. In 1948, he received his Ph.D. degree in
physiology from the University of Chicago, where he had
studied under Dr. Ralph W. Gerard.
Since that time, Dr. Ling has been engaged, without
interruption, in research while successively holding the
positions of Seymour Coman Post-Doctoral Fellow at the
University of Chicago, Instructor at the Johns Hopkins
School of Medicine, Assistant and Associate Professor at
the University of Illinois School of Medicine, and Senior
Research Scientist at the Eastern Pennsylvania
Psychiatric Institute. Dr. Ling is presently Director of
the Department of Molecular Biology at Pennsylvania
Hospital.
***
IN SEARCH OF THE
PHYSICAL BASIS OF LIFE
GILBERT N. LING
Pennsylvania Hospital, Philadelphia, Pennsylvania
"The image [of science] has been previously drawn...
from the study of finished scientific achievements as
these are recorded in the classes and more recently in
the textbooks... Inevitably... a concept of science drawn
from them is no more likely to fit the enterprise that
produced them than an image of national culture drawn
from a tourist brochure or language text."
Thomas Kuhn, The Structure of Scientific
Revolutions
Any scientific investigation is an open-ended, ongoing
process that must continually reevaluate past decisions
and build and expand upon new theories and research
findings. In Search of the Physical Basis of Life
chronicles the history of scientific efforts to
understand the living cell - the basic unit of all life -
and presents the foundation of a new paradigm in cell
physiology, the association-induction (A-I) hypothesis.
Dr. Ling's monumental treatise considers the rise to
dominance of the membrane pump theory and then builds a
solid framework for the A-I hypothesis, citing the
reasons that led to its brief introduction in 1952 and a
detailed version ten years later. The A-I hypothesis
suggests that cellular ions are adsorbed on anionic
protein side chains and that intracellular water is
adsorbed in multilayers on polypeptide chains in the
cell, so that the components of a cell exist in a
dynamically ordered and functionally coherent array. In
addition to the historical and theoretical development of
the A-I hypothesis, Dr. Ling presents results of the
extensive worldwide testing of alternate theories that
has been carried out over the past thirty years.
Distinguished by its all-inclusive approach to a science
that reaches across the natural boundaries of time and
the man-made boundaries of specialized fields, this
unique volume synthesizes old and new information of
great overall significance.
For those who anticipate that progress in cell physiology
may soon match that in genetics and for those who simply
need a more useful set of basic concepts in bio-logical
and medical research, this book is a must.
***
A REVOLUTION IN THE PHYSIOLOGY
OF THE
LIVING CELL
GILBERT N. LING
Full text [DjVu]
"Dr. Ling's work is sophisticated and essential. This book will
guide its readers to the new era of genuine biology."
Dr. Hiroshia Tamagawa, Gifu University, Gifu, Japan
***
LIFE AT THE CELL AND BELOW-CELL LEVEL.
THE HIDDEN HISTORY OF A FUNDAMENTAL REVOLUTION IN BIOLOGY
GILBERT N. LING
"Life on earth is in increasing danger. In my view, if
Gilbert N. Ling's association-induction hypothesis is widely taught to
the younger generation, we could have a much better chance
to save
life on earth".
Prof. Miklós
Kellermayer, University of Péch, Péch,
Hungary
Ling’s Ideas and Their
Importance for Biology and Medicine
(Russian scientists about Ling's book)
Some important Gilbert Ling's articles in PDF format
are available here:
Physiological
Chemistry and Physics and Medical NMR
Last publication:
Ling G.N.
A Convergence of Experimental and Theoretical Breakthroughs Affirms the
PM theory of Dynamically Structures Cell Water on the Theory's 40th
Birthday. In: Water and the Cell. (Pollack G.H., Cameron I.L. and
Wheatley D.N., eds.). Springer, 2006, p. 1-52.
Список трудов Гильберта
Линга
Авторы,
придерживавшиеся тех или иных
аспектов фазово-сорбционного
подхода
Список
публикаций с критикой взглядов
Линга
Новая
книга Гильберта Линга
"Life at the Cell and Below-Cell level. The Hidden History of a
Fundamental Revolution in Biology"
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